The five-day festival will celebrate the people, stories and ideas of science in all its forms.
It will take place across the city, September 13-17, offering over 100 free events, installations and activities.
Encompassing science in the broadest sense, the programme promises something for everyone, regardless of knowledge level.
Whether you're looking to spend the whole day at the festival, or just occupy yourself for a couple of hours, you'll be able to explore the events around the city and on campus.
One of the programme's highlights is 'The Compass' - created by Illuminos, this spellbinding installation is driven by British research pioneers and the everyday person’s life journey. It represents our shared navigation of knowledge, discovery, and the science that shapes our world.
Visitors will be able to explore its interior by day, and marvel at its spectacular exterior by night.
For those interested in a spot of stargazing, the BBC will be recording an episode of their much-loved programme, The Sky at Night. Hosted by Maggie Aderin-Pocock, Pete Lawrence and Chris Lintott, visitors will have the opportunity to join the live audience.
For those interested in a more relaxing, canal-side experience, 'Calming Canoe Journeys' provides the chance to hop in a canoe and paddle downstream.
'Paddleboard Yoga' allows you to let off some steam while perfecting your downward dog. These will be part of The Canal & River Trust's '5 Ways to Wellbeing' series.
All events will take place throughout Leicester in the city centre and on the DMU campus.
Events are scheduled throughout the day and into the evening from Tuesday 13 to Saturday 17 September.
All tickets for the British Science Festival are completely free, but spaces are limited so booking is essential for most events.
Ticket bookings and the full programme line-up can be found online.